MaxCyte’s Flow Electroporation™ Technology is an enabling technology with superior performance, flexibility and scalability which allow it to uniquely fulfill the demands of drug discovery, protein production and cell therapy applications.
Flow Electroporation™ Technology is based on a fundamental principle of cell membranes – the reversible permeability of membranes in the presence of an electrical field – thereby creating a universal transfection technology capable of high-performance delivery of virtually any molecule(s), including DNA, RNA, proteins and cell lysates, to any cell type with minimal cell disturbance.
Our scientists have developed robust electroporation protocols optimized for more than 80 different cell types as well as protocols that can be used to identify the optimum parameters for virtually all other cell types. Flow Electroporation Technology transfects any cell type using a single, chemically-defined electroporation buffer. It causes minimal cell disturbance, routinely resulting in cell viabilities and transfection efficiencies >90 percent, which exceed those of other transfection methods.
Flow Electroporation Technology is a universal technology able to deliver any molecule(s), regardless of size, to cells – DNA, mRNA, gRNA, siRNA, nucleic acid/protein complexes, proteins and cell lysates enabling endless applications.
The process for performing small- and large-scale electroporation are both completed in four easy steps: mixing of cells and loading agent, transferring to a processing assembly, electroporation and cell recovery.