Application Notes & Technical Papers

Rapid Production of Cells for Screening Voltage-Gated Ion Channels in Automated Electrophysiology Assays Using the MaxCyte® STX™ Scalable Transfection System

Comprising a family with hundreds of members, ion channels represent one of the largest classes of drug targets. Recent advances in automated electrophysiology instrumentation have led to the routine implementation of high throughput assays for screening ion channel modulators. However, despite improvements to analytical throughput, hurdles to the development of drugs for ion channel targets still remain.

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