Scientific Publications

Development of anti-human mesothelin-targeted chimeric antigen receptor (CAR) messenger RNA (mRNA)-transfected peripheral blood lymphocytes (CARMA-hMeso) for ovarian cancer therapy CRISPR-Cas9 Gene Repair of Hematopoietic Stem Cells from Patients with X-linked Chronic Granulomatous Disease

CRISPR-Cas9 Gene Repair of Hematopoietic Stem Cells from Patients with X-linked Chronic Granulomatous Disease

Scientific Translational Medicine

9:372 2017. doi: 10.1126/scitranslmed.aah3480

Efficient mRNA-based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-induced ADCC against Lymphoma and Targets NK cell Migration Towards the Lymph Node Associated Chemokine CCL19 Targeted Gene Addition in Human CD34+ Hematopoietic Cells for Correction of X-linked Chronic Granulomatous Disease Effect of Tyrphostin AG879 on Kv4.2 and Kv4.3 Potassium Channels

Effect of Tyrphostin AG879 on Kv4.2 and Kv4.3 Potassium Channels

British Journal of Pharmacology

(2015) 172: 3370-3382

Development of ‘Enhanced’ Potency Immunotherapy Products Using Nonviral Approaches Clinical Scale Zinc Finger Nuclease-Mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma Endothelial NO-Synthase Gene-Enhanced Progenitor Cell Therapy for Pulmonary Arterial Hypertension: The PHACeT Trial CHO-S Antibody Titers >1 Gram/Liter Using Flow Electroporation-Mediated Transient Gene Expression followed by Rapid Migration to High-Yield Stable Cell Lines CAR Window

CAR Window


April 27 2015

Shifting the Balance

Shifting the Balance

European Biopharmaceutical Review

Autumn 2014

Mesothelin-specific Chimeric Antigen Receptor mRNA-engineered T Cells Induce Anti-tumor Activity in Solid Malignancies A Pilot Study of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination Combined With Sunitinib For Metastatic Renal Cell Carcinoma Yellow Fluorescent Protein-Based Assay to Measure GABAA Channel Activation and Allosteric Modulation in CHO-K1 Cells Immunotherapy of Autologous Tumor Lysate-loaded Dendritic Cell Vaccines by a Closed-flow Electroporation System for Solid Tumors Clinical Scale Electroloading of Mature Dendritic Cells with Melanoma Whole Tumor Cell Lysate is Superior to Conventional Lysate Co-incubation in Triggering Robust In Vitro Expansion of Functional Antigen-specific CTL Regimen-specific Effects of RNA-modified Chimeric Antigen Receptor T Cells in Mice with Advanced Leukemia Large Volume Flow Electroporation of mRNA: Clinical Scale Process Efficient Large Volume Lentiviral Vector Production Using Flow Electroporation (PubMed Abstract) Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells Multiple Injections of Electroporated Autologous T Cells Expressing a Chimeric Antigen Receptor Mediate Regression of Human Disseminated Tumor (PDF) Expression of Chimeric Antigen Receptors in Natural Killer Cells with a Regulatory-compliant Non-viral Method (PDF) Delivery of Whole Tumor Lysate into Dendritic Cells for Cancer Vaccination Electroporation Protocols: Preclinical and Clinical Gene Medicine (PDF) Modifying Stem Cells for Clinical Regenerative Applications (PDF) Rapid and Efficient Nonviral Gene Delivery of CD154 to Primary Chronic Lymphocytic Leukemia Cells Efficient Responses in a Murine Renal Tumor Model by Electroloading Dendritic Cells With Whole-Tumor Lysate (PDF) Rescue of Monocrotaline-Induced Pulmonary Arterial Hypertension Using Bone Marrow–Derived Endothelial-Like Progenitor Cells (PDF) Selective Field Effects on Intracellular Vacuoles and Vesicle Membranes with Nanosecond Electric Pulses (PDF) Tech Review: A Scalable Cell-Loading System for Non-Viral Gene Delivery and Other Applications (PDF) Rapid, In Vivo, Evaluation of Antiangiogenic and Antineoplastic Gene Products by Nonviral Transfection of Tumor Cells Highly Efficient, Large Volume Flow Electroporation (PDF)

Highly Efficient, Large Volume Flow Electroporation (PDF)

Technology in Cancer Research & Treatment

Volume 1(5), October 2002

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